Vardenafil Tablets
^ "Staxyn - New Innovation in Erectile Dysfunction Helps Younger Men Rise to the Occasion". U.S.
What special dietary instructions should I follow?
Severe liver disease: It’s not recommended to take vardenafil if you have severe liver disease. In many cases, lowering your vardenafil dosage can help manage these interactions. Vardenafil’s labeling gives specific dosage adjustments for certain interactions, as detailed in the table below. This is not a complete list of vardenafil interactions. You should share an up-to-date medication list with your prescriber and pharmacist.
What do I need to tell my doctor BEFORE I take this drug?
This can help them check for potential interactions. Taking too much vardenafil may raise your risk of side effects, such as headache or back pain. Some people have reported temporary vision problems after taking more vardenafil than recommended. But certain side effects could become dangerous, such as low blood pressure which could cause you to feel dizzy or faint. If you’ve taken too much vardenafil, contact your prescriber for guidance.
What should I do if I miss a dose of vardenafil?
You can also call Poison Control at 1-800-222-1222. But if anything seems severe or life threatening, call 911 or go to the nearest ER. There are ways to save on vardenafil, which is only available as a generic medication. GoodRx can help you save over 80% off the average retail price of the generic version. The price for five of the 10 mg vardenafil tablets at certain pharmacies is as low as $25.04 with a free GoodRx discount. Food and Drug Administration (FDA).
| Dosage (mg) | Typical Usage | Onset of Action | Duration of Effect |
|---|---|---|---|
| 10 | Mild to moderate ED | 30-60 minutes | Up to 4 hours |
| 20 | Moderate to severe ED | 30-60 minutes | Up to 4-5 hours |
| 5 | Lower dose for less side effects | 30-60 minutes | Up to 4 hours |
| 25 | Off-label use, clinical trials | 30-60 minutes | Up to 4 hours |
^ Tucker J, Fischer T, Upjohn L, Mazzera D, Kumar M (October 2018). "Unapproved Pharmaceutical Ingredients Included in Dietary Supplements Associated With US Food and Drug Administration Warnings". Vardenafil is used to treat erectile dysfunction (impotence; inability to get or keep an erection) in men. Vardenafil is in a class of medications called phosphodiesterase (PDE) inhibitors. It works by increasing blood flow to the penis during sexual stimulation. This increased blood flow can cause an erection.
| Product | Dosage | Quantity + Bonus | Price | |
|---|---|---|---|---|
| Levitra Professional | 20mg | 180 + 4 Pills | 502.31€ 478.39€ | |
| Kamagra Effervescent Tablets | 100 mg | 42 + 7 Pills | 122.97€ 117.11€ | |
| Priligy Generic Dapoxetine | 60mg | 120 + 10 Pills | 341.26€ 325.01€ | |
| Levitra Generic | 10mg | 20 Pills | 46.54€ 44.32€ | |
| Tadalista Super Active | 20mg | 180 + 20 Pills | 521.59€ 496.75€ | |
| Viagra Generic | 100mg | 60 + 4 Pills | 96.36€ 91.77€ | |
| Cialis Soft Tabs | 20mg | 20 + 2 Pills | 66.98€ 63.79€ | |
| Levitra Generic | 10mg | 60 + 6 Pills | 112.98€ 107.60€ | |
| Cialis Generic | 10mg | 60 + 6 Pills | 105.81€ 100.77€ | |
| Viagra Generic | 50mg | 180 + 8 Pills | 158.82€ 151.26€ |
Vardenafil does not cure erectile dysfunction or increase sexual desire.
- Vardenafil is available in tablet form, usually 5-20 mg.
- It is designed to be taken as needed, not regularly.
- Effects may vary based on age and health condition.
- Always follow your healthcare provider’s instructions.
Vardenafil does not prevent pregnancy or the spread of sexually transmitted diseases such as human immunodeficiency virus (HIV). This medication may be prescribed for other uses; ask your doctor or pharmacist for more information. Vardenafil comes as a tablet and a rapidly disintegrating (dissolves in the mouth and is swallowed without water) tablet to take by mouth. It is usually taken as needed, with or without food, 60 minutes before sexual activity. Vardenafil usually should not be taken more often than once every 24 hours. If you have certain health conditions or are taking certain medications, your doctor may tell you to take vardenafil less often. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand.
7.2 Effect of Other Drugs on Vardenafil
"Potency, selectivity, and consequences of nonselectivity of PDE inhibition". "Effects of ceridaviescampaigner co uk vardenafil administration on intravaginal ejaculatory latency time in men with lifelong premature ejaculation". "Counseling Patients About Sexual Issues: Drug-Induced Priapism". ^ "FDA Announces Revisions to Labels for Cialis, Levitra and Viagra". Archived from the original on July 9, 2009. Do not take more or less of it or take it more often than prescribed by your doctor. If you are taking the rapidly disintegrating tablet, check the blister pack before you take your first dose. Do not use any of the medication from the pack if any of the blisters are torn, broken, or do not contain tablets. Follow the package directions to remove the tablet from the blister package.
- Vardenafil is effective for up to 4-5 hours.
- Do not use if allergic to vardenafil or similar drugs.
- Overdose symptoms may include prolonged erections.
- Medical advice is essential for any severe side effects.
Do not try to push the tablet through the foil. After you remove the tablet from the blister package, immediately place it on your tongue and close your mouth. Do not take the rapidly disintegrating tablet with water or other liquids. Your doctor will probably start you on an average dose of vardenafil tablets and increase or decrease your dose depending on your response to the medication. If you are taking the rapidly disintegrating tablets, your doctor will not be able to adjust your dose because the rapidly disintegrating tablets are only available in one strength. If you need a higher or lower dose, your doctor may prescribe the regular tablets instead. Tell your doctor if vardenafil is not working well or if you are experiencing side effects. Vardenafil rapidly disintegrating tablets cannot be substituted for vardenafil tablets.
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"Pharmacology and drug interaction effects of the phosphodiesterase 5 inhibitors: focus on alpha-blocker interactions". "The QT Interval and Selection of Alpha-Blockers for Benign Prostatic Hyperplasia". ^ "New erectile dysfunction treatment Staxyn approved in the U.S. - Pharmaceutical Processing". Archived from the original on April 6, 2012. Be sure that you receive only the type of vardenafil that was prescribed by your doctor. Ask your pharmacist if you have any questions about the type of vardenafil you were given. tell your doctor and pharmacist if you are allergic to vardenafil,any other medications. or any of the ingredients in vardenafil tablets. Ask your pharmacist for a list of the ingredients. do not take vardenafil if you are taking or have recently taken riociguat (Adempas) or nitrates such as isosorbide dinitrate (Dilatrate-SR, Isordil, in BiDil), isosorbide mononitrate (Monoket), and nitroglycerin (Minitran, Nitro-Dur, Nitromist, Nitrostat, others).
- Vardenafil is sometimes prescribed off-label for pulmonary hypertension.
- It is not suitable for women or children.
- Patients should report any unexplained vision loss.
- Avoid using grapefruit juice with vardenafil.
Nitrates come as tablets, sublingual (under the tongue) tablets, sprays, patches, pastes, and ointments. Ask your doctor if you are not sure if any of your medications contain nitrates. do not take street drugs containing nitrates such as amyl nitrate and butyl nitrate ('poppers') while taking vardenafil. some medications should not be taken with vardenafil.
5.2 Potential for Drug Interactions with Strong or Moderate CYP3A4 Inhibitors
The typical starting vardenafil dosage for erectile dysfunction is 10 mg by mouth about 1 hour before sex. If needed, your dosage can be raised up to a maximum of 20 mg per day. You should only take vardenafil once a day, regardless of what dose you’ve been prescribed. Adults ages 65 and older may need to take a lower vardenafil dosage to reduce the risk of side effects. The same can be said for people with liver disease or if you take certain interacting medications.
Sensitive determination of anticancer drug imatinib in spiked human urine samples by differential pulse voltammetry on anodically pretreated boron-doped diamond electrode
Your prescriber can help you figure out the best vardenafil dosage for you. Vardenafil, sold under the brand name Levitra among others, is a medication that is used for treating erectile dysfunction. Vardenafil's indications and contraindications are the same as with other PDE5 inhibitors; it is closely related in function to sildenafil citrate (Viagra) and tadalafil (Cialis). The difference between the vardenafil molecule and sildenafil citrate is a nitrogen atom's position and the change of sildenafil's piperazine ring methyl group to an ethyl group. Tadalafil is structurally different from both sildenafil and vardenafil.
Available Strengths (2)·Most prescribed
Vardenafil's relatively short effective time is comparable to but somewhat longer than sildenafil's. Despite the structural differences between vardenafil and sildenafil, they both show similar ocular side effects due to their similar selectivity overlap with PDE6, an enzyme found in the eye. Beyond its indications for erectile dysfunction, vardenafil may be effective in the treatment of premature ejaculation, where it may significantly increase the time from penetration to ejaculation. The common, adverse drug reactions (side effects) are the same as with other PDE5 inhibitors. The frequent vardenafil-specific side-effect is nausea; the infrequent side effects are abdominal pain, back pain, photosensitivity, abnormal vision, eye pain, facial edema, hypotension, palpitation, tachycardia, arthralgia, myalgia, rash, itch, and priapism. Other medications may cause dosing changes or extra monitoring when taken with vardenafil.
- Vardenafil should be stored at room temperature.
- Keep out of reach of children and pets.
- Notify your doctor if you experience priapism.
- Use only the prescribed dose to prevent adverse effects.
Make sure you have discussed any medications you are currently taking or plan to take before starting vardenafil with your doctor and pharmacist. Before starting, stopping, or changing any medications while taking vardenafil, please get the advice of your doctor or pharmacist.
| Side Effect | Frequency | Severity | Recommended Action |
|---|---|---|---|
| Headache | Common | Mild | Take analgesics, hydration |
| Flushing | Common | Mild | Cool environment, hydrate |
| Nasal Congestion | Moderate | Mild | Use decongestants if needed |
| Dizziness | Less common | Mild | Sit or lie down immediately |
| Muscle Pain | Rare | Mild | Consult doctor if persists |
the following herbal product may interact with vardenafil: St. John's wort. Be sure to let your doctor and pharmacist know that you are taking these medications before you start taking vardenafil.
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One possibly serious, but rare, side effect with vardenafil is heart attack. Also, in rare cases, vardenafil use may cause priapism, a very painful emergency condition that can cause impotence if left untreated. In October 2007, the U.S. Food and Drug Administration (FDA) announced that a warning about possible deafness (sudden hearing loss) would be added to the drug labels of vardenafil, and other PDE5 inhibitors. Vardenafil should not be used by people taking nitrate medications, because combining them with vardenafil might provoke potentially life-threatening hypotension (low blood pressure).
Other Interactions
Further, vardenafil causes lengthening of the QT interval. Therefore, it should not be taken by people taking other medications that affect the QT interval (such as amiodarone). Vardenafil was co-marketed by Bayer Pharmaceuticals, GlaxoSmithKline, and Schering-Plough under the brand name Levitra. As of 2005, the co-promotion rights of GSK on Levitra have been returned to Bayer in many markets outside the US. Thus, because of European Union trade rules, parallel imports might result in Vivanza sold next to Levitra in the EU.
Professional resources
An orally disintegrating form, marketed as Staxyn and Levitra Soft, has been gaining approvals in countries such as the United States[11] and Canada. The US Food and Drug Administration (FDA) has found vardenafil and other synthetic PDE5 inhibitors in numerous products marketed as "herbal" supplements or "all natural" products for male enhancement. ^ a b c d "Levitra (vardenafil hydrochloride) tablets, for oral use Initial U.S. Approval: 2003". ^ "Levitra (Vardenafil) is A Drug Used to Treat Erectile Problems in Men" (in German). Do not start any of these medications while taking vardenafil without discussing with your healthcare provider.