Precautions and Warnings Before Starting Treatment

It is unknown if drinking alcohol will affect tadalafil. The risk of low blood pressure and dizziness may be increased if you drink alcohol while taking tadalafil. It is best to limit the amount of alcohol you drink while taking tadalafil.

Ingredient	Quantity per Tablet	Function
Tadalafil	10 mg	Erectile Dysfunction
Dapoxetine	60 mg	Premature Ejaculation
Excipients	varies	Tablet Stabilization
Magnesium Stearate	2 mg	Lubricant in manufacturing

Always tell your healthcare provider about any prescription or over-the-counter (OTC) medicines, vitamins/minerals, herbal products, and other supplements you are using.

Contacts and Locations

What are the serious side effects of tadalafil?

In particular, make sure that you discuss if you are using any of the following before taking tadalafil. A nitrate, such as nitroglycerin (Nitro-Dur, Nitrostat, and others) or isosorbide, which is a medicine used for chest pain caused by a type of heart disease, or a street drug, such as amyl nitrite (“poppers”) A guanylate cyclase stimulator, such as riociguat (Adempas), which is a medicine used for high blood pressure in the lungs (pulmonary arterial hypertension), or vericiguat (Verquvo), which is a medicine used for a type of heart failure An alpha-blocker, such as alfuzosin (Uroxatral), doxazosin (Cardura), dutasteride, prazosin (Minipress), silodosin (Rapaflo), tamsulosin (Flomax), or terazosin (Hytrin), which is a medicine that may be used for high blood pressure and/or difficulty peeing due to an enlarged prostate A blood pressure medicine, such as amlodipine (Norvasc) or enalapril (Vasotec) Bosentan (Tracleer), which is a medicine used for pulmonary arterial hypertension A protease inhibitor, such as ritonavir (Norvir), which is a medicine commonly used to treat HIV Rifampin (Rifadin), which is a medicine commonly used to treat an infection called tuberculosis A medicine used for fungal infections, such as ketoconazole or itraconazole (Sporanox, Tolsura) Erythromycin (Ery-Tab and others) or clarithromycin (Biaxin), which is a medicine used for bacterial infections Any other medicine used for erectile dysfunction or pulmonary arterial hypertension Some other medicines may alter the blood levels of tadalafil.

Product	Dosage	Quantity + Bonus	Price
Cialis Generic	10mg	120 + 6 Pills	178.49€ 169.99€	Buy
Priligy Generic Dapoxetine	60mg	60 + 8 Pills	183.06€ 174.34€	Buy
Priligy Generic Dapoxetine	60mg	30 + 6 Pills	106.65€ 101.57€	Buy
Priligy Generic Dapoxetine	60mg	10 Pills	47.63€ 45.36€	Buy
Viagra Professional	100mg	270 + 6 Pills	456.97€ 435.21€	Buy
Cialis Professional	20mg	360 + 6 Pills	807.03€ 768.60€	Buy
Priligy Generic Dapoxetine	60mg	120 + 10 Pills	341.26€ 325.01€	Buy
Tadalista Super Active	20mg	60 + 8 Pills	230.32€ 219.35€	Buy
Cialis Generic	20mg	360 + 10 Pills	427.34€ 406.99€	Buy
Kamagra Soft Tabs	100mg	180 + 8 Pills	425.45€ 405.19€	Buy
Priligy Generic Dapoxetine	60mg	20 + 4 Pills	77.31€ 73.63€	Buy
Priligy Generic Dapoxetine	60mg	180 + 10 Pills	494.76€ 471.20€	Buy
Priligy Generic Dapoxetine	60mg	90 + 10 Pills	265.64€ 252.99€	Buy

Tell your healthcare provider about all medicines that you take or have recently taken.

Alternate Names

It is unknown if drinking alcohol will affect tadalafil. The risk of low blood pressure and dizziness may be increased if you drink alcohol while taking tadalafil. It is best to limit the amount of alcohol you drink while taking tadalafil. Always tell your healthcare provider about any prescription or over-the-counter (OTC) medicines, vitamins/minerals, herbal products, and other supplements you are using. In particular, make sure that you discuss if you are using any of the following before taking tadalafil.

Consult Your Healthcare Provider

A nitrate, such as nitroglycerin (Nitro-Dur, Nitrostat, and others) or isosorbide, which is a medicine used for chest pain caused by a type of heart disease, or a street drug, such as amyl nitrite (“poppers”) A guanylate cyclase stimulator, such as riociguat (Adempas), which is a medicine used for high blood pressure in the lungs (pulmonary arterial hypertension), or vericiguat (Verquvo), which is a medicine used for a type of heart failure An alpha-blocker, such as alfuzosin (Uroxatral), doxazosin (Cardura), dutasteride, prazosin (Minipress), silodosin (Rapaflo), tamsulosin (Flomax), or terazosin (Hytrin), which is a medicine that may be used for high blood pressure and/or difficulty peeing due to an enlarged prostate A blood pressure medicine, such as amlodipine (Norvasc) or enalapril (Vasotec) Bosentan (Tracleer), which is a medicine used for pulmonary arterial hypertension A protease inhibitor, such as ritonavir (Norvir), which is a medicine commonly used to treat HIV Rifampin (Rifadin), which is a medicine commonly used to treat an infection called tuberculosis A medicine used for fungal infections, such as ketoconazole or itraconazole (Sporanox, Tolsura) Erythromycin (Ery-Tab and others) or clarithromycin (Biaxin), which is a medicine used for bacterial infections Any other medicine used for erectile dysfunction or pulmonary arterial hypertension Some other medicines may alter the blood levels of tadalafil. Tell your healthcare provider about all medicines that you take or have recently taken. This may not be a complete list of medicines that can interact with tadalafil. If you or someone else has used too much tadalafil, get medical help right away, call 911, or contact a Poison Control center at 800-222-1222. If it is almost time for your next dose, skip the missed dose and only take the next dose.

Standard Dosage

Do not dapoxetine 30mg tablet take double or extra doses. Some tadalafil products are meant to be used only when needed. Take it as your healthcare provider recommends. This survey is being conducted by the WebMD marketing sciences department. May 16, 2022 updated by: Neutec Ar-Ge San ve Tic A.Ş The purpose of this study is to evaluate the safety and efficacy of Dapoxetine/Tadalafil 30/20 mg film-coated tablet in the treatment of men with premature ejaculation and erectile dysfunction. This may not be a complete list of medicines that can interact with tadalafil. If you or someone else has used too much tadalafil, get medical help right away, call 911, or contact a Poison Control center at 800-222-1222. If it is almost time for your next dose, skip the missed dose and only take the next dose. Do not dapoxetine 30mg tablet take double or extra doses. Some tadalafil products are meant to be used only when needed. Take it as your healthcare provider recommends. This survey is being conducted by the WebMD marketing sciences department. May 16, 2022 updated by: Neutec Ar-Ge San ve Tic A.Ş The purpose of this study is to evaluate the safety and efficacy of Dapoxetine/Tadalafil 30/20 mg film-coated tablet in the treatment of men with premature ejaculation and erectile dysfunction. This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Does dapoxetine affect testosterone levels?

and other conditionsIraq Rigicon, Inc.RecruitingErectile Dysfunction (ED)United States University College, LondonRecruitingRadical Prostatectomy Erectile Dysfunction Following Radical Prostatectomy Erectile Dysfunction Due to Arterial Insufficiency Robotic Radical ProstatectomyUnited Kingdom Valenta Pharm JSCCompletedInfluenza, Human Common Cold Acute Respiratory InfectionRussian Federation Neutec Ar-Ge San ve Tic A.ŞCompletedErectile Dysfunction Premature EjaculationTurkey Merck Sharp & Dohme LLCCompletedHuman Immunodeficiency Virus-1 (HIV-1) H. Lundbeck A/SCompletedBioequivalence Study in Healthy SubjectsRussian Federation Product Name : Super Carefill Tadalafil & Dapoxetine Tablet Available Dosage : 20mg + 30mg, 20mg + 60mg, 40mg + 60mg Therapeutic use : helps men to obtain and sustain erections by relaxing blood vessels Introduction to Super Carefill Tadalafil & Dapoxetine Tablet Super Carefill is an advanced medication that merges Tadalafil, a well-known phosphodiesterase type 5 (PDE5) inhibitor, with Dapoxetine, a selective serotonin reuptake inhibitor (SSRI). This combination is formulated to treat both erectile dysfunction and premature ejaculation, offering a dual benefit for improved sexual health.

Q8: Can women take Dapoxetine + Tadalafil?

Study Major Dates

Istanbul, TurkeyOkmeydanı Training and Research Hospital Urology Dep. Contact:Mehmet Gokhan Culha, DrPhone Number: 0000 00902123145555Email: gokhan_culha64@hotmail.com Istanbul, TurkeyOkmeydanı Training and Research Hospital Urology Dep. Contact:Mehmet Gokhan Culha, DrPhone Number: 0000 00902123145555Email: gokhan_culha64@hotmail.com Okmeydanı Training and Research Hospital Urology Dep. Contact:Mehmet Gokhan Culha, DrPhone Number: 0000 00902123145555Email: gokhan_culha64@hotmail.com Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments. Participants must be heterosexual males and in a stable monogamous sexual relationship with a female partner for at least 6 months and will continue throughout the study, Clinical diagnosis of erectile dysfunction, IIEF score ≤21, Premature Ejaculation Diagnostic Tool (PEDT) score must be ≥11 Patients with life-long PE and acquired PE according to the description of International Society for Sexual Medicine (ISSM) , The patient and his partner must have sexual intercourse twice a week for the duration of the study, Commitment to comply with the study protocol, Patients who sign informed consent form (ICF). History of medical events such as surgical interventions or neurologic conditions (e.g., multiple sclerosis), trauma, or infections that are associated with the development of symptoms of premature ejaculation (PE) and considered a potential cause of PE, Having genital abnormalities, except penile curvature unless not prevent sexual intercourse, Developed erectile dysfunction or premature ejaculation due to drug use or quit taking drugs, Any conditions that prevent sexual intercourse with partners History of in last 6 months stroke, myocard infarction, cardiac insufficiency (New York Cardiovascular Associates (NYCA) phase II-IV), atrioventricular block or message disorder such as sick sinus syndrome, severe ischemic cardiac disease, syncope, unstable angina, life-threatening arrhythmia or hypotension, Patients who are not eligible to have sexual intercourse due to existing health problems, Autonomic neuropathy, retinitis pigmentosa, blood diseases, active peptic ulcer, abnormalities in ECG, severe systemic disease that cannot be controlled, Systolic/Diastolic blood pressure at rest <90/50 mmHg and 170/100 mmHg< History of allergy to Selective Serotonin Reuptake Inhibitor (SSRI) and phosphodiesterase inhibitor drugs, Continuing to use or quitted in last 3 months of Monoamine oxidase inhibitor (MAOI), Thioridazine, Serotonin Reuptake Inhibitor (SSRI), Selective-norepinephrine Reuptake Inhibitor (SNRI), Serotonergic drug/herbal product, tricyclic antidepressant and atypical antipsychotic drugs, Use of nitrates, alfa blockers, vasodilators, ketoconazole, itraconazole, ritonavir, saquinavir, telithromycin, nefazodone, nelfinavir, atazanavir, cimetidine, erythromycin, clarithromycin, fluconazole, amprenavir, fosamprenavir, aprepitant, verapamil, diltiazem, any kind of vasodilator, antiplatelet, anticoagulant, dapoxetine, phosphodiesterase 5 inhibitor, alcohol and stimulant drug, Patients on a different therapy (behavioral therapy or other drugs that are applied locally) for PE treatment During the study, the possibility of taking medication which may affect the study drug's pharmacokinetic/pharmacodynamic properties Patients who are defining symptoms of prostatitis clinically This section provides details of the study plan, including how the study is designed and what the study is measuring. This is where you will find people and organizations involved with this study.

Parameter	Tadalafil	Dapoxetine
Absorption Time	30-120 minutes	1-3 hours
Peak Plasma Concentration	2 hours	1-2 hours
Half-life	17.5 hours	19 hours
Metabolism	Liver (CYP3A4)	Liver (CYP2D6, CYP3A4)

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov.

Study/Source	Efficacy Percentage	Sample Size	Notes
Clinical Trial A	85%	200 patients	Improved erectile function, reduced PE
Patient Surveys	78%	500 users	Satisfaction with combined therapy
Meta-Analysis	82%	Multiple Studies	Overall effectiveness for ED and PE

Study records and reported dapoxetine 5mg results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

• Common side effects include lightheadedness, nasal congestion, or stomach upset.
• Serious side effects, though rare, include vision changes or allergic reactions.
• Do not use if you have a history of severe hypotension or stroke.
• Alcohol consumption may impair the effectiveness and increase side effects.
• Use this medication only under medical supervision and guidance.
• Always read the patient leaflet for detailed instructions and warnings.

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well. Taksim Egitim ve Arastirma HastanesiActive, not recruitingErectile Dysfunction Vascular Erectile Dysfunction Atherogenic DyslipidemiaTurkey (Türkiye) Labbafinejad Medical CenterNot yet recruitingErectile Dysfunction Erectile Dysfunction Due to General Medical Condition Erectile Dysfunction Due to Arterial Insufficiency Erectile Dysfunction Associated With Type 2 Diabetes Mellitus Erectile Dysfunction Due to Arterial Disease Erectile Dysfunction Due to NeuropathyIran Ryan Flannigan, MDRecruitingErectile Dysfunctions Erectile Function Erectile Dysfunction (ED)Canada Cairo UniversityRecruitingErectile Dysfunction Erectile Dysfunction Following Radical Prostatectomy Erectile Dysfunction Following Simple Prostatectomy Erectile Dysfunction With Diabetes Mellitus Erectile Dysfunction Due to Arterial Disease Erectile Dysfunction Due to Injury Erectile Dysfunction Due to Neuropathy and other conditionsEgypt Mansoura University HospitalNot yet recruitingErectile Dysfunction Due to Venous Disorder Erectile Dysfunction (ED) University of VirginiaActive, not recruitingErectile Dysfunction Erectile Dysfunction Following Radical Prostatectomy Erectile Dysfunction Following Radiation Therapy Erectile Dysfunction Due to General Medical Condition Erectile Dysfunction Due to Arterial InsufficiencyUnited States University of BaghdadCompletedSexual Dysfunction Erectile Dysfunction Erectile Dysfunction Following Radical Prostatectomy Erectile Dysfunction Following Radiation Therapy Sexual Abstinence Erectile Dysfunction With Diabetes Mellitus Sexual Desire Disorder Erectile Dysfunction Following Cryotherapy Erectile Dysfunction..

• Tadalafil and dapoxetine are usually taken 30-60 minutes before sex.
• The combination can be used on demand or as prescribed by a doctor.
• Patients should report any prolonged erections or severe side effects immediately.
• The medication should not be used with nitrates or certain blood pressure medicines.
• Pregnant or breastfeeding women should avoid using these tablets.
• Proper storage away from moisture and heat preserves drug efficacy.

and other conditionsIraq Rigicon, Inc.RecruitingErectile Dysfunction (ED)United States University College, LondonRecruitingRadical Prostatectomy Erectile Dysfunction Following Radical Prostatectomy Erectile Dysfunction Due to Arterial Insufficiency Robotic Radical ProstatectomyUnited Kingdom Valenta Pharm JSCCompletedInfluenza, Human Common Cold Acute Respiratory InfectionRussian Federation Neutec Ar-Ge San ve Tic A.ŞCompletedErectile Dysfunction Premature EjaculationTurkey Merck Sharp & Dohme LLCCompletedHuman Immunodeficiency Virus-1 (HIV-1) H.

About the Company

This section provides the contact details for those conducting the study, and information on where this study is being conducted. Istanbul, TurkeyOkmeydanı Training and Research Hospital Urology Dep. Contact:Mehmet Gokhan Culha, DrPhone Number: 0000 00902123145555Email: gokhan_culha64@hotmail.com Istanbul, TurkeyOkmeydanı Training and Research Hospital Urology Dep. Contact:Mehmet Gokhan Culha, DrPhone Number: 0000 00902123145555Email: gokhan_culha64@hotmail.com Okmeydanı Training and Research Hospital Urology Dep. Contact:Mehmet Gokhan Culha, DrPhone Number: 0000 00902123145555Email: gokhan_culha64@hotmail.com Researchers look for people who fit a certain description, called eligibility criteria.

Q5: How does Dapoxetine + Tadalafil work?

Some examples of these criteria are a person's general health condition or prior treatments. Participants must be heterosexual males and in a stable monogamous sexual relationship with a female partner for at least 6 months and will continue throughout the study, Clinical diagnosis of erectile dysfunction, IIEF score ≤21, Premature Ejaculation Diagnostic Tool (PEDT) score must be ≥11 Patients with life-long PE and acquired PE according to the description of International Society for Sexual Medicine (ISSM) , The patient and his partner must have sexual intercourse twice a week for the duration of the study, Commitment to comply with the study protocol, Patients who sign informed consent form (ICF). History of medical events such as surgical interventions or neurologic conditions (e.g., multiple sclerosis), trauma, or infections that are associated with the development of symptoms of premature ejaculation (PE) and considered a potential cause of PE, Having genital abnormalities, except penile curvature unless not prevent sexual intercourse, Developed erectile dysfunction or premature ejaculation due to drug use or quit taking drugs, Any conditions that prevent sexual intercourse with partners History of in last 6 months stroke, myocard infarction, cardiac insufficiency (New York Cardiovascular Associates (NYCA) phase II-IV), atrioventricular block or message disorder such as sick sinus syndrome, severe ischemic cardiac disease, syncope, unstable angina, life-threatening arrhythmia or hypotension, Patients who are not eligible to have sexual intercourse due to existing health problems, Autonomic neuropathy, retinitis pigmentosa, blood diseases, active peptic ulcer, abnormalities in ECG, severe systemic disease that cannot be controlled, Systolic/Diastolic blood pressure at rest <90/50 mmHg and 170/100 mmHg< History of allergy to Selective Serotonin Reuptake Inhibitor (SSRI) and phosphodiesterase inhibitor drugs, Continuing to use or quitted in last 3 months of Monoamine oxidase inhibitor (MAOI), Thioridazine, Serotonin Reuptake Inhibitor (SSRI), Selective-norepinephrine Reuptake Inhibitor (SNRI), Serotonergic drug/herbal product, tricyclic antidepressant and atypical antipsychotic drugs, Use of nitrates, alfa blockers, vasodilators, ketoconazole, itraconazole, ritonavir, saquinavir, telithromycin, nefazodone, nelfinavir, atazanavir, cimetidine, erythromycin, clarithromycin, fluconazole, amprenavir, fosamprenavir, aprepitant, verapamil, diltiazem, any kind of vasodilator, antiplatelet, anticoagulant, dapoxetine, phosphodiesterase 5 inhibitor, alcohol and stimulant drug, Patients on a different therapy (behavioral therapy or other drugs that are applied locally) for PE treatment During the study, the possibility of taking medication which may affect the study drug's pharmacokinetic/pharmacodynamic properties Patients who are defining symptoms of prostatitis clinically This section provides details of the study plan, including how the study is designed and what the study is measuring. This is where you will find people and organizations involved with this study. These dates track the progress of study record and summary results submissions to ClinicalTrials.gov.

Rare but Serious Side Effects

Study records and reported dapoxetine 5mg results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website. This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well. Taksim Egitim ve Arastirma HastanesiActive, not recruitingErectile Dysfunction Vascular Erectile Dysfunction Atherogenic DyslipidemiaTurkey (Türkiye) Labbafinejad Medical CenterNot yet recruitingErectile Dysfunction Erectile Dysfunction Due to General Medical Condition Erectile Dysfunction Due to Arterial Insufficiency Erectile Dysfunction Associated With Type 2 Diabetes Mellitus Erectile Dysfunction Due to Arterial Disease Erectile Dysfunction Due to NeuropathyIran Ryan Flannigan, MDRecruitingErectile Dysfunctions Erectile Function Erectile Dysfunction (ED)Canada Cairo UniversityRecruitingErectile Dysfunction Erectile Dysfunction Following Radical Prostatectomy Erectile Dysfunction Following Simple Prostatectomy Erectile Dysfunction With Diabetes Mellitus Erectile Dysfunction Due to Arterial Disease Erectile Dysfunction Due to Injury Erectile Dysfunction Due to Neuropathy and other conditionsEgypt Mansoura University HospitalNot yet recruitingErectile Dysfunction Due to Venous Disorder Erectile Dysfunction (ED) University of VirginiaActive, not recruitingErectile Dysfunction Erectile Dysfunction Following Radical Prostatectomy Erectile Dysfunction Following Radiation Therapy Erectile Dysfunction Due to General Medical Condition Erectile Dysfunction Due to Arterial InsufficiencyUnited States University of BaghdadCompletedSexual Dysfunction Erectile Dysfunction Erectile Dysfunction Following Radical Prostatectomy Erectile Dysfunction Following Radiation Therapy Sexual Abstinence Erectile Dysfunction With Diabetes Mellitus Sexual Desire Disorder Erectile Dysfunction Following Cryotherapy Erectile Dysfunction.. Lundbeck A/SCompletedBioequivalence Study in Healthy SubjectsRussian Federation Product Name : Super Carefill Tadalafil & Dapoxetine Tablet Available Dosage : 20mg + 30mg, 20mg + 60mg, 40mg + 60mg Therapeutic use : helps men to obtain and sustain erections by relaxing blood vessels Introduction to Super Carefill Tadalafil & Dapoxetine Tablet Super Carefill is an advanced medication that merges Tadalafil, a well-known phosphodiesterase type 5 (PDE5) inhibitor, with Dapoxetine, a selective serotonin reuptake inhibitor (SSRI). This combination is formulated to treat both erectile dysfunction and premature ejaculation, offering a dual benefit for improved sexual health.